Disease: Renal glomerular disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZMPSTE24 O75844 zinc metallopeptidase STE24 Enzyme 8.9E-16 0.517 0.731
YWHAZ P63104 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta Chaperone 0.94 0.475 0.846
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VANGL2 Q9ULK5 VANGL planar cell polarity protein 2 0.84 0.588 0.615
TYRP1 P17643 tyrosinase related protein 1 Enzyme 6.6E-25 0.507 0.846
TYRO3 Q06418 TYRO3 protein tyrosine kinase Kinase 8.3E-10 0.559 0.769
TRPC6 Q9Y210 transient receptor potential cation channel subfamily C member 6 Ion channel 3.0E-07 0.514 0.692
TRPC5 Q9UL62 transient receptor potential cation channel subfamily C member 5 Ion channel 1.00 0.653 0.615
TRNL1 tRNA 0.534 0.731
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TBPL1 P62380 TATA-box binding protein like 1 Transcription factor 0.38 0.506 0.846
SYNPO Q8N3V7 synaptopodin Cellular structure 0.99 0.663 0.577
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
SMARCAL1 Q9NZC9 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 2.3E-06 0.599 0.654
SMAD7 O15105 SMAD family member 7 Transcription factor 0.55 0.470 0.769
SLC5A2 P31639 solute carrier family 5 member 2 Transporter 4.9E-14 0.499 0.769
SLC12A3 P55017 solute carrier family 12 member 3 Transporter 3.0E-32 0.493 0.808
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SCN7A Q01118 sodium voltage-gated channel alpha subunit 7 Ion channel 2.2E-17 0.585 0.692
SCARB2 Q14108 scavenger receptor class B member 2 Receptor 8.9E-05 0.606 0.615
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962